Tom Brown Group

High throughput measurement of duplex, triplex and quadruplex melting curves using molecular beacons and a LightCycler

R. A. J. Darby, M. Sollogoub, C. M. McKeen, L. Brown, A. Risitano, N. Brown, C. Barton, T. Brown and K. R. Fox. Nucleic Acids Res. 30 (9), e39, 2002.

Mode of action and application of Scorpion primers to mutation detection

N. Thelwell, S. Millington, A. Solinas, J. Booth and T. Brown. Nucleic Acids Res. 28 (19), 3752-3761, 2000.

The orientation and dynamics of the C2'-OH and hydration of RNA and DNA-RNA hybrids

J. I. Gyi, A. N. Lane, G. L. Conn and T. Brown. Nucleic Acids Res. 26 (13), 3104-3110, 1998.

Crystal structure of a G : T/U mismatch-specific DNA glycosylase: Mismatch recognition by complementary-strand interactions

T. E. Barrett, R. Savva, G. Panayotou, T. Barlow, T. Brown, J. Jiricny and L. H. Pearl. Cell 92 (1), 117-129, 1998.

Structural basis of DNA mutagenesis

T. Brown and O. Kennard. Curr. Opin. Struct. Biol. 2 (3), 354-360, 1992.

The Incorporation of 2,6-Diaminopurine Into Oligodeoxyribonucleotides by the Phosphoramidite Method

T. Brown, E. D. Booth and A. G. Craig. Nucleosides Nucleotides 8, 1051, 1989.

Structure of an adenine-cytosine base pair in DNA and its implications for mismatch repair

W. N. Hunter, T. Brown, N. N. Anand and O. Kennard. Nature 320 (6062), 552-555, 1986.

The crystal structure of d(GGGGCCCC) a model for poly (dG) · poly (dC)

M. McCall, T. Brown and O. Kennard. J. Mol. Biol. 183 (3), 385-396, 1985.

Loosening the DNA wrapping around single-walled carbon nanotubes by increasing the strand length

Q. H. Yang, Q. Wang, N. Gale, C. J. Oton, L. Cui, I. S. Nandhakumar, Z. Zhu, Z. Tang, T. Brown and W. H. Loh. Nanotechnology 20 (19), 195603, 2009.

Thermodynamic Aspects of DNA Nanoconstruct Stability and Design

P. Sandin, J. Tumpane, K. Borjesson, L. M. Wilhelmsson, T. Brown, B. Norden, B. Albinsson and P. Lincoln. J. Phys. Chem. C 113 (15), 5941-5946, 2009.

The stability of triplex DNA is affected by the stability of the underlying duplex

D. A. Rusling, P. A. Rachwal, T. Brown and K. R. Fox. Biophys. Chem. 145 (2-3), 105-110, 2009.

DNA triplex formation with 5-dimethylaminopropargyl deoxyuridine

D. A. Rusling, G. M. Peng, N. Srinivasan, K. R. Fox and T. Brown. Nucleic Acids Res. 37 (4), 1288-1296, 2009.

The Use of an Electroactive Marker as a SERS Label in an E-melting Mutation Discrimination Assay

S. Mahajan, J. A. Richardson, N. Ben Gaied, Z. Y. Zhao, T. Brown and P. N. Bartlett. Electroanalysis 21 (20), 2190-2197, 2009.

Flexible Acoustic Particle Manipulation Device with Integrated Optical Waveguide for Enhanced Microbead Assays

P. Glynne-Jones, R. J. Boltryk, M. Hill, F. Zhang, L. Dong, J. S. Wilkinson, T. Melvin, N. R. Harris and T. Brown. Anal. Sci. 25 (2), 285-291, 2009.

Multi-modal particle manipulator to enhance bead-based bioassays

P. Glynne-Jones, R. J. Boltryk, M. Hill, F. Zhang, L. Dong, J. S. Wilkinson, T. Brown, T. Melvin and N. R. Harris. International Congress on Ultrasonics, Santiago, Chile 3, 269-275, 2009.

Synthesis and Polymerase Chain Reaction Amplification of DNA Strands Containing an Unnatural Triazole Linkage

A. H. El-Sagheer and T. Brown. J. Am. Chem. Soc. 131 (11), 3958-3964, 2009.

Platform for Controlled Supramolecular Nanoassembly

I. Czolkos, J. K. Hannestad, A. Jesorka, R. Kumar, T. Brown, B. Albinsson and O. Orwar. Nano Lett. 9 (6), 2482-2486, 2009.

Structural analysis of the DNA target site and its interaction with Mbp1

A. V. Chernatynskaya, L. Deleeuw, J. O. Trent, T. Brown and A. N. Lane. Org. Biomol. Chem. 7 (23), 4981-4991, 2009.

Membrane-Anchored DNA Assembly for Energy and Electron Transfer

K. Borjesson, J. Tumpane, T. Ljungdahl, L. M. Wilhelmsson, B. Norden, T. Brown, J. Martensson and B. Albinsson. J. Am. Chem. Soc. 131 (8), 2831-2839, 2009.

Nucleic Acid Base Analog FRET-Pair Facilitating Detailed Structural Measurements in Nucleic Acid Containing Systems

K. Borjesson, S. Preus, A. H. El-Sagheer, T. Brown, B. Albinsson and L. M. Wilhelmsson. J. Am. Chem. Soc. 131 (12), 4288-4293, 2009.