Tom Brown Group

Nucleic Acids Research

Interdisciplinary Research

Our research is interdisciplinary, focusing on nucleic acid chemistry and its applications in other fields including DNA diagnostics, forensic science and nanotechnology.

Over 350 research papers and patents

Our publications have been cited more than 14000 times.

Commercialization

Our research has led to the foundation of three companies, as well as the development of several new technologies in collaboration with industrial partners.

Latest news

5-Formylcytosine shown not to change the global structure of DNA

May 16th, 18:13

In a paper published in Nat. Struct. Mol. Biol., we have shown that, contrary to previous observations, 5-formylcytosine does not significantly alter DNA structure

Latest paper

RPA activates the XPF-ERCC1 endonuclease to initiate processing of DNA interstrand crosslinks

Jun 12th, 2017

U. B. Abdullah, J. F. McGouran, S. Brolih, D. Ptchelkine, A. H. El-Sagheer, T. Brown and P. J. McHugh. EMBO J. 2017.

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Contact

Tom Brown

Professor of Nucleic Acid Chemistry

University of Oxford

E-mail: tom...@chem.ox.ac.uk

Address

Chemistry Research Laboratory
Mansfield Road
Oxford
OX1 3TA

Join the group!

We are always looking for enthusiastic, hard-working people. If you are interested, please contact us.

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