Six-Colour HyBeacon Probes for Multiplex Genetic Analysis

J. A. Richardson, M. Gerowska, M. Shelbourne, D. J. French and T. Brown. ChemBioChem 11 (18), 2530-2533, 2010.

Abstract

A combination of six HyBeacon probes has been used in multiplex genetic analysis to analyse mutations in the CFTR gene of PCR-amplified human DNA. Multicolour HyBeacons of this type have great potential in human genetic screening and point-of-care diagnosis.

View paper

Latest paper

A new phosphoramidite enables orthogonal double labelling to form combination oligonucleotide probes

Oct 27th, 2022

Chunsen Bai, Piotr Klimkowski, Cheng Jin, Jagannath Kuchlyan, Afaf H. El-Sagheer* and Tom Brown*. Org. Biomol. Chem. 20, 8618-8622, 2022.