Tom Brown Group

Nucleic Acids Research

We have a postdoctoral position to fill in nucleic acid chemistry

Apr 11th 2023, 13:42

.. in the synthesis of modified oligonucleotides. You will join the International TransNAT consortium to transform delivery, safety and efficacy of nucleic acid therapeutics. Good synthetic chemistry skills are essential.

An LNA-amide modification that enhances the cell uptake and activity of phosphorothioate exon-skipping oligonucleotides

Ysobel Baker, Cameron Thorpe, Jinfeng Chen, Laura Poller, Lina Cox, Pawan Kumar, Wooi Fang Lim, Lillian Lie, Graham McClorey, Sven Epple, Daniel Singleton, Michael McDonough, Jack Hardwick, Kirsten Christensen, Matthew Wood, James Hall, Afaf El-Sagheer, Tom Brown. Nature Communications 13 (1), 1-11, 2022.